selective oral ATR kinase inhibitor
in Ph. I for adv. solid tumors and lymphomas
from HTS and modeling on PI3Kg structure
J. Med. Chem., Jun. 5, 2020
Bayer AG, Berlin, DE
BAY 1895344
BAY 1895344 is a potent and highly selective inhibitor of the ATR kinase, which is involved in the DNA damage response. Further disruption of the DNA damage response via ATR…