Structure of ATR inhibitor BAY 1895344

selective oral ATR kinase inhibitor

in Ph. I for adv. solid tumors and lymphomas

from HTS and modeling on PI3Kg structure

J. Med. Chem., Jun. 5, 2020

Bayer AG, Berlin, DE

BAY 1895344 is a potent and highly selective inhibitor of the ATR kinase, which is involved in the DNA damage response. Further disruption of the DNA damage response via ATR…

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