oral CXCR3 antagonist

efficacy in mice model of lung inflammation

from HTS and opt

J. Med. Chem.

Idorsia Pharmaceuticals Ltd., Allschwil, CH

ACT-660602 chemical structure oral CXCR3 antagonist - Idorsia Pharmaceuticals Ltd., Allschwil, CH

Context. ACT-660602 (Idorsia Pharmaceuticals) is an oral chemokine receptor CXCR3 antagonist being developed for autoimmune diseases. Chemokines and their receptors make up the signaling system that is responsible for…


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