BD2 domain selective BET inhibitor
orally efficacious in XG w/o platelet, GI tox
from SBDD of BD1/2 dual inhibitors
Nature, 2020, 578, 306-310
AbbVie, North Chicago, IL
ABBV-744
1 min read
ABBV-744 (AbbVie oral in vivo BD2 domain selective BET inhibitor)
Search By Structure
- LNP023
- LMB763 (nidufexor)
- ABBV-744
- AG-881
- FT-2102 (olutasidenib)
- GS-9876 (lanraplenib)
- “compound 25”
- “compound 25”-2
- WF-47-JS03
- BMS-986260
- GNF2133
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