Momelotinib, an oral JAK1/2 inhibitor for myelofibrosis, is going to GSK as part of a $1.9 billion acquisition of Sierra Oncology. Anyone that’s ever worked on a kinase program probably looked at this structure and raised their eyebrows. $1.9 billion for another JAK2 inhibitor? It’s probably not super selective either, you might think… and you’d be right. But details here are actually pretty interesting.
this content is exclusive to
Upgrade to a Premium Drug Hunter membership to unlock the full content and start reading now.