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Mar. 30, 2024

KT-474: The First Clinically Active Heterobifunctional Degrader Outside Oncology

KT-474

oral IRAK4 degrader Ph. II in AD and HS from SBDD of ligands for CRBN, IRAK4, and linker Nature Medicine, Nov. 2023 Kymera Therapeutics, Watertown, MA

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