Chemical structure of molecule HR011303

human uric acid transporter inhibitor

phase III candidate for hyperuricemia and gout

from pharmacophore-based lead generation

Drug Metabolism and Disposition

Jiangsu Hengrui Medicine Co., Shanghai, CN

Gout is caused by the buildup of uric acid. The main treatments are drugs that increase uric acid secretion (uricosurics, e.g. probenecid) and xanthine oxidase inhibitors which inhibit uric…

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