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gut-restrict. P-gp inh. for oral paclitaxel combo
efficacious in Ph. III, NDA filed but CRL issued
from opt. of tariquidar
J. Med. Chem., Mar. 17, 2021
Athenex / Hanmi Pharmaceutical, Seoul, KR
The Athenex/Hanmi Pharmaceutical P‑gp transporter inhibitor (encequidar) is a gut-restricted compound intended to reduce efflux and increase absorption of the IV drug, paclitaxel to enable oral paclitaxel delivery. The…
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