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RBP4 reducer targeting RBP4/TTR PPI
preclinical, in vivo RBP4 reduction
from HTS and optimization
Bioorganic and Medicinal Chemistry
Takeda, Fujisawa, JP
Retinol-binding protein 4 (RBP4) is the sole carrier for retinol (vitamin A). It may also play a role in diabetes and reduction of RBP4 may be beneficial for the…
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