Chemical structure of molecule compound 43b Retinol-binding protein 4 (RBP4)

RBP4 reducer targeting RBP4/TTR PPI

preclinical, in vivo RBP4 reduction

from HTS and optimization

Bioorganic and Medicinal Chemistry

Takeda, Fujisawa, JP

Retinol-binding protein 4 (RBP4) is the sole carrier for retinol (vitamin A). It may also play a role in diabetes and reduction of RBP4 may be beneficial for the…

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