© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
New Drug Hunter content, featured events and job postings straight to your inbox. Trusted by >3,500 drug hunters worldwide, unsubscribe anytime.
<< Back to March
mutant alpha-1-antitrypsin folding corrector
sub-µM in cell, high predicted human %F
from 2T component DEL + SBDD
Bioorg. Med. Chem. Lett., Mar. 19, 2021
GlaxoSmithKline, Stevenage, UK / UCL
The GlaxoSmithKline (GSK) Z α1-antitrypsin stabilizer (“compound 13,” GSK716) acts by blocking the formation of polymers within the endoplasmic reticulum of hepatocytes for treatment of α1-antitrypsin deficiency. It was…
Ask your company or librarian about a Drug Hunter membership to to see all summaries and get access to even more helpful information.