Oral RORy nuclear receptor antagonist

on-going Ph. II for psoriasis (QD dosing)

50k cmpd high-conc. frag. screen + scaff. hop

ACS Med. Chem. Lett., Jan. 5, 2021

Boehringer Ingelheim, Ridgefield, CT

The Boehringer RORγ antagonist, BI 730357, is an oral once-daily clinical candidate from a new compound class in development for plaque psoriasis. We highlighted two other RORγ modulators last…


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