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EMA Approval: Lenacapavir (Sunlenca), a First-In-Class HIV Capsid Inhibitor

In August 2022, the European Medicines Agency granted Marketing Authorization to lenacapavir (Sunlenca), the first-in-class bi-annually dosed HIV capsid inhibitor indicated for multidrug-resistant HIV-1 infection.

This Premium deep dive into Sunlenca includes:

  • the industry context
  • the clinical data
  • the target rationale
  • the mechanism of action
  • the drug’s origins
lenacapavir (Sunlenca), HIV capsid inhibitor, Twice yearly injection after a 2-week oral loading, For adults with multidrug-resistant HIV-1 infection, Gilead Sciences
Lenacapavir (Sunlenca), chemical structure

See our overview of all 36 of the novel small molecule and large molecule FDA approvals for 2022 here.

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