This section contains case studies, industry highlights, minireviews, and other articles for drug discovery professionals. Check out the resources page for posters, educational content, lists of drug approvals, and more.
By Daniel Beck and Karson Putt Edited by Dennis X. Hu, Nicholas Morano, Jen Huen Reviewed by Pablo MartÃn-Gago, Ravi…
resource
3 weeks ago ●
31 mins read
A CNS-Penetrant KRASG12C Inhibitor Intended for CNS-Metastatic Cancers AZD4747 is a CNS-penetrant, oral KRASG12C covalent inhibitor for the treatment of…
molecule
3 weeks ago ●
7 mins read
An oral GLP-1R agonist competing with peptide injectables for diabetes and obesity. Peptidic GLP-1R agonists have received significant media coverage…
molecule
4 weeks ago ●
13 mins read
A potential best-in-class TRβ agonist prodrug for NASH demonstrates impressive efficacy and safety. Thyroid hormone receptor β (TRβ, THRβ or…
molecule
4 weeks ago ●
7 mins read
Targeting 20-HETE/GPR75 via Selective CYP Inhibition: A 20+ Year-Old Kidney Program from Taisho The arachidonic acid (AA) metabolite, 20-hydroxy-5,8,11,14-eicosatetranoic acid…
molecule
1 month ago ●
5 mins read
An Active Prodrug, Triple Reuptake Inhibitor for Major Depressive Disorder While SNRIs and selective serotonin reuptake inhibitors (SSRIs) have been…
molecule
1 month ago ●
11 mins read
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