© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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oral serine _-lactamase inh. prodrug
restores ceftibuten activity in model, Ph. I
hydrolysis transition state mimetic
Journal of Medicinal Chemistry
Venatorx Pharmaceuticals, Malvern, US
11. The Venatorx serine _-lactamase inhibitor VNRX-7145 is an orally bioavailable prodrug of the boronic acid-containing inhibitor VNRX-5236, and is currently in Ph. I. It demonstrates activity in vitro…
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