Feb. 25, 2023

A metabolite and its parent: same target inhibition, different mechanisms.

PF-6870961

GHSR1a inverse agonist (metabolite of oral molecule) Ph. Ia for heavy alcohol drinking major hydroxy metabolite of PF-5190457 JPET, January 11, 2023 NIDA/NIAAA, NIH (Pfizer)

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MOTY Nominees

Molecule of the Year