potential best-in-class CETP inh. (<1 mg QD)
completed Ph. I in HV; discont. as backup
from anacetrapib
Journal of Medicinal Chemistry
Merck & Co., Kenilworth, NJ, USA
MK-8262
The Merck CETP inhibitor backup, MK-8262, is potential best-in-class CETP inhibitor, which was only discontinued as a backup due to the success of its predecessor, anacetrapib in Ph. III. Reviewer Kim…