© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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monocarboxylate transporter 4 inhibitor
in vivo PD but limited eff. in xenograft model
from cell-based screen and opt.
Journal of Medicinal Chemistry
Merck Healthcare KGaA, Darmstadt, Germany
The Merck KGaA MCT4 chemical probe, “compound 18n”, is a novel inhibitor of the monocarboxylate transporter MCT4. Large quantities of lactic acid need to be transported out of tumor cells…
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