oral once-daily sGC activator

Ph. II for CKD + diabetic neuropathy

from cell-based HTS + opt

J. Med. Chem., Apr. 19, 2021

Bayer AG, Wuppertal, DE

The Bayer soluble guanylate cyclase (sGC) activator, BAY 1101042 (runcaciguat), is a once-daily (50 mg), oral clinical candidate in Ph. II for chronic kidney disease and diabetic retinopathy. sGC is…

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