ACT-777991, an oral and insurmountable CXCR3 antagonist discovered by Idorsia (formerly Actelion), is under investigation for the treatment of Type 1 Diabetes (T1D). Despite the complex history of CXCR3 antagonists, ACT-777991 has shown promise with [...]
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May 11, 2023
ACT-777991: Next-Generation CXCR3 Antagonist in Phase I Trials for Type 1 Diabetes
ACT-777991
oral reversible CXCR3 antagonist Ph. I in healthy subjects opt. of known CXCR3 antagonists J. Med. Chem., March 8, 2023 Idorsia Pharmaceuticals Ltd, CH