Mirati/Array/Pfizer KRAS(G12D) inhibitor
oral, BID, reversible KRAS(G12D) inhibitor entering Ph. I/II for KRAS(G12D)-mutated tumors from SBDD of KRASG12C inhibitor MRTX1133 Mirati Therapeutics, San Diego, CA; Pfizer, Boulder, CO (formerly Array)
Molecules of the Month - 2022 Molecules of the Year Nominees
- BMS TYK2 inhibitor
- Mirati/Array/Pfizer KRAS(G12D) inhibitor
- Madrigal THRβ-selective agonist
- GBT/Pfizer HbS polymerization inhibitor
- Myokardia/BMS cardiac myosin inhibitor
- Kura Oncology menin-MLL1 inhibitor
- LEO Pharma IL-17A modulator
- YourChoice/UMN RAR-α antagonist
- Cerevel/Pfizer M4 positive allosteric modulator
- ChemoCentryx C5aR antagonist
- BMS TYK2 inhibitor
- Mirati/Array/Pfizer KRAS(G12D) inhibitor
- Madrigal THRβ-selective agonist
- GBT/Pfizer HbS polymerization inhibitor
- Myokardia/BMS cardiac myosin inhibitor
- Kura Oncology menin-MLL1 inhibitor
- LEO Pharma IL-17A modulator
- YourChoice/UMN RAR-α antagonist
- Cerevel/Pfizer M4 positive allosteric modulator
- ChemoCentryx C5aR antagonist