This page provides a list of curated industry service providers (contract research organizations) that provide outsourced contract drug discovery services of particular interest to drug discovery professionals working at biotechs or pharmaceutical companies.
The table below lists drug discovery CROs specializing in all kinds of drug discovery services, from X-ray crystallography CROs to CROs specializing in assay development, to integrated drug discovery CROs. You can search and explore the table for CRO specializations from chemistry to solid form development to physicochemical property measurement to protein purification and protein crystallization.
If your company would like to be included in this list of drug discovery CROs, contact us with the information for the table.
| Company | Relevant Specialty | |||
|---|---|---|---|---|
| Selvita | https://www.selvita.com | CRO | 780 | Selvita is a fully-integrated CRO providing multidisciplinary support from target validation to the selection of clinical candidates, medicinal chemistry, in vitro and in vivo pharmacology, structural biology, ADME, pharmacokinetics, and toxicology. |
| Venenum Biodesign | https://drughunters.com/3Dsoo7q | CRO | 28 | Expertise in assay development, compound profiling, 5.5 million ECLiPS Compound library, hit-to-lead, lead optimization, protein production & structural biology, ADME & bioanalytical services |
| Comparative Bioscience, Inc | https://drughunters.com/3z9S72C | CRO | 26 | Expertise in preclinical in vivo studies, surgical and efficacy models, biocompatibility & devices, toxicology, pharmacokinetics, pharmacology, efficacy, GLP & non-GLP studies, in-house histopathology and immunohistochemistry |
| BioBlocks | https://drughunters.com/3gGI6DG | CRO | 19 | A medicinal chemistry CRO focused on drug discovery from initial hit through identification of development candidates for advancement to phase II clinical trials using our fragment-based Leap-to-Leadâ„¢ platform & Syntheverseâ„¢ chemistry space. |
| Invivotek | https://drughunters.com/3sqcswA | CRO | 18 | CRO specializing in the evaluation of therapeutic candidates in rodent models of human disease, animal models and bioassays, in vivo testing of compounds related to Immunology and Inflammation, Oncology, Metabolic, Cardiovascular and other diseases |
| PharmOptima | https://drughunters.com/3MYmBu0 | CRO | 10 | CRO services include in vivo studies, DMPK/ADME, ocular PD/efficacy, bioanalytical, ligand binding & biological/analytical assays, molecular biology & biochemistry, biomarker & assay dev. Specializing in therapeutic areas in ocular drug development |
| New England Drug Discovery Partners | https://drughunters.com/3N3f9xu | CRO | 13 | Expertise in discovery chemistry, medicinal chemistry, structure-based drug design, organic synthesis, analytical services, antibody drug conjugates (ADC), process chemistry and scale-up capabilities |
| Integrated Analytical Solutions | https://drughunters.com/3gEnQCB | CRO | 8 | Expertise in GLP & non-GLP bioanalytical services, in vitro metabolism, metabolite ID, drug-drug interaction, protein binding, and plasma stability assays, analytical chemistry, release & stability, NCDFA, physiochemical profiling, and assay dev. |
| NexusPharma | https://drughunters.com/3W7qhxs | CRO | 1 | Expertise in patient-derived xenograft (PDX) models, cell line-derived xenograft (CDX), syngenic models, & preclinical cancer models of various tumor types for in vivo efficacy studies to validate the biological activity of cancer treatment compounds |
| ZoBio | https://drughunters.com/3Hv33wj | CRO | ZoBio offers an integrated fragment-based drug discovery engine based on orthogonal technologies and 18 years of experience. The engine consists of high throughput protein engineering, a highly diverse fragment library, proprietary biophysical technologies and complementary structural biology approaches designed to enable the broadest possible target space. | |
| Charnwood Molecular | https://drughunters.com/3Uj8r97 | CRO | 130 | From target to candidate. Our highly experienced team, covering biology and DMPK through to computational, medicinal and process research chemistry, act together seamlessly to provide the right environment for an integrated solution to drug discovery. |
| BirdoTech | https://drughunters.com/3FKvANW | CRO | 700 | BirdoTech is a chemistry CRO specializing in medchem support with scale-up capabilities and expertise on various chemistry platforms; such as kinases, GPCRs, PROTACs, peptides, and ADCs. These state-of-the-art research labs are located in China and the US. |
| Pharmaron | https://www.pharmaron.com/ | CRO | 14,000 | Synthesis and Preclinical Discovery Services |
| Almac | https://www.almacgroup.com | CRO | 3,082 | API Services, CMC, GMP |
| Evotec | https://www.evotec.com | CRO | 3,030 | High-Throughput Screening, Preclinical Discovery Services |
| Sai Life Sciences | https://www.sailife.com/services/discovery/integrated-drug-discovery-services/ | CRO | 2,500 | Integrated Drug Discovery Services, Exploratory Biology, Discovery Chemistry, DMPK, Toxicology, Genotox., and Comp. Chem. |
| Promega | https://worldwide.promega.com/ | CRO | 2,500 | Cell-Based and Biochemical Assays, Custom Assay |
| MedChemExpress | https://www.medchemexpress.com/ | CRO | 2,500 | Relevant specialty: Small Molecules, Recombinant Proteins, Screening Libraries, Custom Synthesis |
| Aragen | https://www.aragen.com/ | CRO | 2,500 | Chemistry CRO and CDMO |
| Viva | https://www.vivabiotech.com/ | CRO | 2000 | Drug discovery one-stop CMC and CDMO service partner |
| AMRI | https://www.amriglobal.com | CRO | 2,077 | Synthesis and Preclinical Discovery Services, GMP |
| WuXi AppTec | https://www.wuxiapptec.com/ | CRO | 22,233 | An integrated chemistry and biology research platform to create, identify and support preclinical candidates, from discovery to development. |
| TCG Lifesciences | https://www.tcgls.com/ | CRO | 1,200 | Synthesis and Preclinical Discovery Services |
| Nuvisan | https://www.nuvisan.com/home.html | CRO | 1,000 | Integrated Drug Discovery CRO |
| Novasep | https://www.novasep.com/ | CRO | 866 | Custom Synthesis, API Manufacturing, Membrane Filtration |
| Pharma Resources | https://www.pharmaresources.cn | CRO | 850 | Focusing on chemistry related CRO/CDMO/CMO services |
| Eurofins | https://www.eurofins.com/ | CRO | 17,158 | Assay Panels |
| ChemPartner | https://www.chempartner.com/ | CRO | 738 | Synthesis and Preclinical Discovery Services |
| Frontage Laboratories | https://www.frontagelab.com/ | CRO | 737 | Pharmaceutical Biotech Drugs |
| BioLegend | https://www.biolegend.com/ | CRO | 549 | Antibodies, Flow Cytometry, Immunoassay kits |
| Charles River | https://www.criver.com/ | CRO | 10,608 | In Vitro and In Vivo Pre-clinical Research Models |
| Almelo | http://almelochem.com/ | CRO | 500 | Custom Synthesis, cGMP Manufacturing, Biocatalysis |
| Symeres | https://symeres.com/ | CRO | 500 | Integrated drug discovery & API development |
| Cayman Chemical | https://www.caymanchem.com/ | CRO | 500 | Preclinical Discovery, Lipidomics, Synthesis, GM |
| Sygnature Discovery | https://www.sygnaturediscovery.com | CRO | 500 | Preclinical services, protein crystallography |
| Bioduro | https://bioduro.com/ | CRO | 428 | Synthesis and Preclinical Discovery Services |
| HitGen | https://www.hitgen.com | CRO | 397 | DNA-Encoded Libraries |
| Crown Bioscience | https://www.crownbio.com | CRO | 350 | In Vitro and In Vivo Pre-clinical Research Models |
| Symeres | https://symeres.com/ | CRO | 329 | Medicinal chemistry, parallel chemistry, API |
| SYNthesis med chem | https://www.synmedchem.com | CRO | 270 | Synthetic & Medicinal Chemistry |
| Schrodinger | https://www.schrodinger.com | CRO | 250 | Computational chemistry software, molecular modeling |
| Cobra Biologics | https://swedenbio.se/medlemmar/cobra-biologics/ | CRO | 250 | DNA, Gene Therapies, Immunotherapies, Viral vectors |
| NuChem Sciences | https://nuchemsciences.com/ | CRO | 240 | Medicinal Chemistry, CMC and Biology |
| Axcelead Drug Discovery Partners, Inc. | https://www.axcelead.com/en/ | CRO | 201 | High-Throughput Screening |
| Nicoya | https://nicoyalife.com/ | CRO | 200 | Diagnostics, Nanotechnology, Sensors, Lifesciences |
| NovAliX | https://www.novalix.com | CRO | 200 | Drug Discovery, Chemistry, Biophysics & Biology |
| LakePharma | https://www.lakepharma.com | CRO | 193 | Protein Sciences |
| Absorption Systems | https://www.absorption.com | CRO | 157 | Preclinical DMPK |
| Paraza | https://parazapharma.com/ | CRO | 155 | Synthesis and Preclinical Discovery Services |
| Genesis Drug Discovery & Development (GD3) | https://gd3services.com/ | CRO | 150 | Integrated Drug Discovery & Development Services |
| X-Chem | https://www.x-chemrx.com | CRO | 120 | DNA-Encoded Libraries |
| Edelris | https://www.edelris.com/ | CRO | 100 | AS-MS screening, Compound collection, Medicinal Chem |
| Reaction Biology | https://www.reactionbiology.com/ | CRO | 80 | Assays |
| Lead Discovery Center | https://www.lead-discovery.de | CRO | 75 | Integrated small molecule drug discovery |
| Vernalis (HitGen) | https://www.vernalis.com/ | CRO | 75 | Fragment and Structure-based Design |
| Solvo | https://www.solvo.com | CRO | 75 | Drug transporter Assays, drug-drug interaction |
| Domainex | https://www.domainex.co.uk/ | CRO | 70 | Preclinical Discovery Services |
| LCC (Liverpool ChiroChem Ltd) | https://liverpoolchirochem.com | CRO | 65 | Chirally-pure scaffolds, fragments and lead |
| Proteros | https://www.proteros.com/ | CRO | 59 | Protein crystallography, Cryo-EM |
| Biognosys | https://www.biognosys.com | CRO | 59 | Proteomic analysis |
| Red Glead Discovery | https://www.redglead.com/ | CRO | 55 | Integrated drug discovery services |
| Iktos | https://iktos.ai/ | CRO | 54 | Artificial intelligence for new drug design |
| BioAscent Discovery Ltd | https://www.bioascent.com/ | CRO | 51 | Drug Discovery |
| SpiroChem | https://www.spirochem.com/ | CRO | 51 | Elite Discovery Chemistry CRO |
| Acme Bioscience | https://www.acmeca.com/ | CRO | 50 | Custom Synthesis |
| Creative Biostructure Drug Discovery | https://drug-discovery.creative-biostructure.com/ | CRO | 50 | Preclinical Discovery Services Based on Structure |
| Pion | https://www.pion-inc.com | CRO | 47 | Analytical services (e.g. LogD) |
| SB Drug Discovery | https://www.sbdrugdiscovery.com/ | CRO | 45 | Assay development, high-throughput screening |
| Specs | https://www.specs.net/ | CRO | 40 | Compound Handling and Chemistry Services |
| DiscoverRX | https://www.discoverx.com/home | CRO | 40 | Assay panels, in vitro screening |
| Apex Molecular Ltd | https://apexmolecular.com/ | CRO | 40 | Small molecule synthesis, high potency synthesis |
| Pelago Bioscience | https://www.pelagobio.com/ | CRO | 38 | CETSA® cellular thermal shift assay |
| Key Organics | https://www.keyorganics.net/ | CRO | 36 | Provision of intermediates, screening compounds |
| J-Star | https://www.jstar-research.com/ | CRO | 34 | Crystallization, formulation, GMP API |
| Visikol | https://visikol.com/ | CRO | 31 | 3D Cell Culture, high content screening |
| Metrion Biosciences | http://www.metrionbiosciences.com | CRO | 30 | Cardiac safety, ion channel assays, assay dev |
| SARomics | https://www.saromics.com | CRO | 25 | Protein crystallography, NMR & fragment screening |
| TCG GreenChem | https://tcggreenchem.com/ | CRO | 25 | Synthesis and Preclinical Discovery Services |
| AIM Biosciences | https://www.aimbiosciences.com/ | CRO | 25 | Custom Synthesis |
| Amuna Pharmaceuticals LLP | http://amunapharma.com/ | CRO | 25 | Synthetic Chemistry, Medicinal Chemistry |
| Chemotargets | https://chemotargets.com/ | CRO | 25 | De novo drug design, prediction of safety and efficacy |
| nanoimagingservices | http://www.nanoimagingservices.com/ | CRO | 24 | CryoEM |
| Hypha Discovery | https://bit.ly/3tte4Wo | CRO | 24 | Drug metabolite synthesis, purification and characterization. We are a specialist CRO supporting pharma companies worldwide through production of metabolites and late-stage drug derivatives. We are experts in scalable synthesis, purification, and identification of metabolites and possess a wealth of experience in the purification and structure elucidation of natural products. |
| Analiza | https://www.analiza.com/ | CRO | 23 | Non-GLP Discovery Screening, Physchem Properties |
| Inoviem | https://www.inoviem.com/ | CRO | 20 | Target ID, MoA on human tissues & patient stratification |
| Pentagrit | http://pentagrit.com | CRO | 15 | Zebrafish efficacy screening, toxicology studies |
| Quintara Discovery | https://qdibio.com/ | CRO | 14 | In vitro ADME, GLP, non-GLP bioanalysis |
| Panlabs (Eurofins) | https://www.eurofinsdiscoveryservices.com/about-us/global-locations/taiwan/ | CRO | 14 | Assay panels |
| R2M Pharma | https://www.r2mpharma.com/ | CRO | 13 | Preclinical drug discovery |
| Asha Pharma | https://ashasd.com/ | CRO | 12 | Solid Form Screening and Selection |
| CrystalsFirst GmbH | https://www.crystalsfirst.com | CRO | 10 | Structure-based drug discovery |
| The Solubility Company | https://www.thesolubilitycompany.com/ | CRO | 10 | Solid Form Specific Solubility Analysis |
| Chemo Dynamics | https://www.chemodynamics.com/ | CRO | 10 | GMP infrastructure focused on small molecules |
| Lotus Separations | http://www.lotusseparations.com/ | CRO | 10 | Chiral separation |
| Pentagrit | https://www.pentagrit.com/ | CRO | 10 | Efficacy screening, toxicity testing, Zebrafish models |
| MAG-LAB | https://www.mag-lab.eu/ | CRO | 10 | protein ligand complexes, protein sciences |
| Accelero Biostructures | http://www.accelerobio.com | CRO | 5 | Structure-based drug discovery |
| Ubiquigent | https://www.ubiquigent.com | CRO | 5 | Deubiquitinating enzyme assays (DUB) and kits |
If your company would like to be included in this list of drug discovery CROs, contact us with the information for the table.
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