Michael Koehler

Michael Koehler received his Ph.D. from Stanford University in 2000, and has been a medicinal chemist at Genentech since that time, working in a variety of therapeutic areas. He was recognized as an ACS Hero of Chemistry in 2017 as part of the team that discovered Vismodegib, and more recently has been working on antibiotic drug discovery, principally on enabling the arylomycins as novel, broad spectrum antimicrobials.

Nirmatrelvir: 2021 Small Molecule of the Year

We asked the global drug discovery community to nominate and vote on their favorite molecule from 2021, and the results are in. The 2021 choice for Drug Hunter’s Small Molecule of the Year is Pfizer’s CoV-2 M pro Inhibitor, PF-07321332 (nirmatrelvir, Paxlovid) . Published in a November 2021 Science article , the molecule was praised for its [...]

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