drughunter.com

Why Did GSK Pay $1.9B for Momelotinib, an Oral Ph. III Myelofibrosis Candidate?

drughunter.com
Drug Hunter Team
Loading...

twitterlinkedinemail

Other articles you may be interested in

KRAS Roundup: Twelve G12C Clinical Molecules to Know

There continue to be opportunities for another KRAS(G12C) inhibitor to prove itself best-in-class.

This roundup highlights twelve KRAS(G12C) molecules to know, with links to recent case studies on Drug Hunter going in more detail.

Drug Hunter 2023 M&A Review: Part 4 - Biologics-Focused Deals

Drug Hunter has sifted through news articles, press releases, financial disclosures, SEC filings, and more to bring you a roundup of 2023’s biggest mergers and acquisitions (M&A) in the drug discovery world. Following our open-access industry overview, in the final installment of this four-part series we bring you the biologics-focused deals opening checkbooks in 2023.

KIN-3248: Overcoming FGFR Resistance with a Next-Generation Pan-FGFR Inhibitor

KIN-3248 (Kinnate Biopharma) is a next-generation, irreversible, pan-fibroblast growth factor receptor inhibitor (FGFRi) in a first-in-human (FIH) dose-escalation study (NCT05242822) in adults with advanced tumors harboring FGFR2 and FGFR3 gene alterations. The program is an excellent case study for rational covalent drug design to address kinase mutations while maintaining sufficient PK properties for oral daily dosing in humans.

August Deals and Funding Rounds Recap

In case you missed August’s business news, here’s a quick recap of five headlines, including an acquisition, three funding rounds, and a notable company closure.

Billion-Dollar Molecules: M4 Modulators, GLP-1 Biased Agonists, and an SSTR2 Radiotherapy

Last December, the pharmaceutical industry witnessed many important updates for clinical molecules, ranging from neurology-based therapies to anti-tumors and radiopharmaceuticals, in addition to the unfortunate discontinuations. In case you missed it, here is a recap of the most notable news updates in the pharma world for December 2023