In April’s edition of Small Molecules of the Month, we have several fascinating molecules including a tri-complex KRAS-ON inhibitor from Revolution Medicines, a targeted protein stabilizer from a Berkeley/Novartis collaboration, and an RNA-modifying enzyme inhibitor from Storm/Cambridge. A slide deck …
There was a hilarious set of memes circulating the internet on scientific papers thanks to xkcd.com’s original comic. Here’s our drug discovery scientist’s parody. Since people expressed an interest in being able to find this again, here it is: Explore …
There were 15 novel large molecule drugs approved in 2020, an increase over the 12 large molecule drugs approved in 2019. Here’s a visual list of the FDA’s 2020 large molecule drug approvals, with more scientific details and references below. …
The March 2021 edition of Drug Hunter‘s Small Molecules of the Month series contains several small molecule clinical candidates as well as pre-clinical small molecules with interesting structures or mechanisms. Among the highlights are LSN3318839, a molecular glue that binds …
February was a packed month for interesting molecules – there were nearly 20 molecules we thought about including in this list but couldn’t fit them all. There are several clinical candidates this month including mobocertinib, an exon 20 mutant inhibitor …
We asked the global drug discovery community to vote on their favorite molecule from 2020, and the results are in. The community’s 2020 choice for Small Molecule of the Year is GS-6207 (lenacapavir), the awe-inspiring HIV capsid inhibitor published by …