In September 2022, deucravacitinib (Sotyktu), a first-in-class oral, allosteric tyrosine kinase 2 (TYK2) inhibitor for moderate-to-severe plaque psoriasis, was approved by the FDA. Aside from its first-in-class mechanism of action, it is the first approved de novo deuterated drug.
This premium deep dive into deucravacitinib includes:
- the industry context
- the clinical data
- the target rationale
- the mechanism of action
- the drug’s origins
See our overview of all 36 of the novel small molecule and large molecule FDA approvals for 2022Â here.
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