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molecules of the month

February 2022

Drug Hunter’s February 2022 Small Molecules of the Month include a glucokinase partial activator, an orexin receptor agonist intended to promote wakefulness rather than sleep, and an orally available diacid, among others.

Thanks to Kim Huard, Julien Lefranc, and Bryan McKibben for their nominations and insights this month.

Is BMS-820132 a prodrug?

How is T-690 different from previous generations of GCS inhibitors?

Which off-target is correlated to loss of appetite in rats?

What were the starting points for these molecules?

Premium Members can find these answers and more in the dedicated summaries and the Member’s slide deck below.

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