For the first installment of Drug Hunter’s “Small Molecules of the Month” series in 2021, we have a Kissei SGLT2 inhibitor whose lead was a metabolite found in mouse urine, a GSK integrin inhibitor that was found to trigger lysosomal degradation, and the first non-sugar OGA inhibitor derived from a Takeda virtual screen. Plenty of interesting reading here to start your year – more details, links, and the PDF download below.
January 2021
- remogliflozin etabonate
- GLPG2451
- BI 730357
- MLi-2
- "compound 1"
- "compound 5i"
- E7386
- NVS-BET-1
- "compound 16"
- JNJ-63576253 / TRC-253
- dosimertinib
- BMS-986242
- CCS1477
- Con B-1