With over two decades of experience in neuroscience drug discovery, Drug Hunter reviewer Jake Schwarz says "mGluR2/3 agonists have been explored for schizophrenia, and agonists/PAMS could be tuned to give antagonist/NAM activity, but depression is a new indication. One of the more interesting depression [...]
6 minute read
Mar. 28, 2023
TP0473292: A mGluR2/3 Antagonist Prodrug
TP0473292
mGluR2/3 antagonist prodrug Ph. II for depression prodrug of TP0178894 (hydrophilic glutamate analog) Drug Metab. Dispos., February 8, 2023 Taisho Pharmaceutical Co., Toyko, JP
Reviewer:
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