S6821

potent and selective TAS2R8 GPCR antagonist

approved non-systemic bitter taste blocker

from 200k cmpd cell-based screen and opt.

J. Med. Chem., Apr. 24, 2020

Firmenich SA, San Diego, CA

S6821 is one of two potent and selective TAS2R8 GPCR antagonists disclosed by Firmenich, a fragrance and flavor company. These compounds block bitter taste receptors and don’t have significant systemic…


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