“PROTAC 6”
IAP-based selective RIPK2 degrader prolonged PD w/ 0.15 mpk SC Q3D dosing E3 binder switch and property-based opt. Commun. Biol., Mar. 20, 2020 GlaxoSmithKline, Stevenage, UK / PMCC
Molecules of the Month - March 2020
Molecules of the Month
- CC-92480
- “PROTAC 6”
- GSK620
- Merck hArg1 inhibitor
- Merck IDO1 inhibitor
- Constellation EZH2 inhibitor
- Arcus CD73 inhibitor
- MK-6884
- sulfopin
- M3814
- remibrutinib