molecules of the month


M4 positive allosteric modulator PET tracer

good uptake and brain signal, BPND = 0.83

from optimatization of prior M4 PAM

J. Med. Chem., Mar. 12, 2020

Merck, West Point, PA

1 min read

MK-6884 (Merck M4 positive allosteric modulator PET tracer) 2022 Update: Human Ph. I data disclosed in https://doi.org/10.1126/scitranslmed.abg3684

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