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M4 positive allosteric modulator PET tracer
good uptake and brain signal, BPND = 0.83
from optimatization of prior M4 PAM
J. Med. Chem., Mar. 12, 2020
Merck, West Point, PA
MK-6884 (Merck M4 positive allosteric modulator PET tracer) 2022 Update: Human Ph. I data disclosed in https://doi.org/10.1126/scitranslmed.abg3684
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