oral gut-restricted bile acid transporter inh.

approved for cholestatic pruritis in Sep. 2021

repurposed (first patented in 1994)

The Lancet

Mirum / Pfizer / Pharmacia / Searle

Chemical structure of molecule Maralixibat Mirum Pharmaceuticals IBAT bile acid transporter inhibitor

The Mirum Pharmaceuticals IBAT bile acid transporter inhibitor, maralixibat, has a long history, having been first patented by scientists at Searle in 1994 and published by the time Searle became part of…


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