oral gut-restricted bile acid transporter inh.
approved for cholestatic pruritis in Sep. 2021
repurposed (first patented in 1994)
The Lancet
Mirum / Pfizer / Pharmacia / Searle
maralixibat
The Mirum Pharmaceuticals IBAT bile acid transporter inhibitor, maralixibat, has a long history, having been first patented by scientists at Searle in 1994 and published by the time Searle became part of…