7 minute read
May 1, 2023

A Furan-Containing Insurmountable Antagonist and Inverse Agonist of the Adenosine A2A Receptor for Parkinson’s Disease

KW-6356

oral A2A receptor antagonist/inverse agonist Ph. II for Parkinson’s Disease 2nd gen. A2A receptor antagonist ASPET, March 9, 2023 Kyowa Kirin Co., Ltd., Shizuoka, JP

drughunter.com
Drug Hunter Team

Kyowa Kirin’s KW-6356, or sipagladenant , is a non-xanthine A 2A receptor intended to treat Parkinson’s disease. Unlike Kyowa Kirin’s recently US-approved neutral antagonist, istradefylline, the molecule is an [...]

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