Chemical structure of molecule JNJ-A07

pan-genotype, pan-serotype dengue virus inh.

high barrier to resistance, efficacious in vivo

from phenotypic antiviral screen

Nature

Janssen Pharmaceutica, Beerse, BE

The Janssen pan-genotype, pan-serotype dengue virus inhibitor, JNJ-A07, demonstrates broad activity against a panel of 21 clinical isolates and has a high barrier to resistance. It blocks the interaction between…


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