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Home > GSK2818713
broad geno. HCV NS5A repl. complex inhibitor
low Cl and orally available in higher species
from rational design from known ligand
J. Med. Chem., Apr. 23, 2020
GlaxoSmithKline, Research Triange Park, NC
GSK2818713 is an HCV NS5A replication complex inhibitor with an interesting biphenylene linker. The crowded, hotly competitive NS5A space has led to a lot of creative chemical scaffolds including this one.
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