© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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GPR84 GPCR negative allosteric modulator
oral Ph. II candidate for IPF
from 200k cmpd biochem. HTS and opt.
J. Med. Chem. Sep. 29, 2020
Galapagos, Romainville, FR / Mechelen, BE
GLPG1205 is a potent, selective, and orally bioavailable negative allosteric modulator of the GPCR GPR84, a receptor associated with inflammation. Despite possessing both a dioxane ring and an relatively unhindered…
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