GPR38 agonist

Ph. I candidate for chronic constipation

from previously disclosed GPR38 agonists

Bioorg. Med. Chem. Lett.

Daiichi Sankyo Co., Ltd.

GPR38 agonist - Daiichi Sankyo Co., Ltd.

DS-3801b is a non-macrolide GPR38 agonist and a Ph. I clinical candidate for treatment of chronic constipation (SAD 1-100 mg PO). GPR38 is the receptor for the GI hormone…


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