© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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bioavailable EP300/CBP HAT inhibitor
brain penetrant, orally efficacious in xeno.
from HTS and SBDD
ACS Med. Chem. Lett., Apr. 27, 2020
Constellation Pharma., Cambridge, MA
CPI-1612 is a pretty efficient-looking EP300/CBP histone acetyltransferase (HAT) inhibitor tool compound with demonstrated activity in a xenograft model and good higher species PK. While epigenetics targets like HATs have…
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