Compound 53 chemical structure, non-nucleotide STING agonist - University of Texas Southwestern Medical Center, Dallas, TX

non-nucleotide STING agonist

novel mechanism for STING activation

from micromolar HTS hit

Nature

University of Texas Southwestern Medical Center, Dallas, TX

Context. ”Compound 53” (University of Texas Southwestern Medical Center) is a stimulator of interferon (IFN) genes (STING) agonist. STING agonists have been heavily pursued in cancer immunology as increasing…


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