oral Factor XIa inhibitor

IV efficacy in rabbit AV shunt model

from literature starting point and SBDD

J. Med. Chem.

Janssen Research & Development, L.L.C., Spring House, PA

Compound 3f Chemical Structure oral Factor XIa inhibitor - Janssen Research & Development, L.L.C., Spring House, PA

Context. “Compound 3f” (Janssen) is an oral Factor XIa (FXIa) inhibitor being developed for thromboembolic diseases. The suitability of FXIa as a target in the development of anticoagulation agents…


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