© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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orally active ChemR23 GPCR inhibitor
oral effects on dendritic cells in higher species
from cell-based screen and optimization
Bioorg. Med. Chem., Jul. 14, 2020
Kyowa Kirin, Shizuoka, JP
“compound 38a” is an inhibitor of ChemR23, a chemokine-receptor-like GPCR with a role in plasmacytoid dendritic cell (pDC) trafficking. The ChemR23 inhibitor was developed with the intention of suppressing the…
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