oral PARP1-selective polymerase inhibitor

oral efficacy in BRCA1 mutant xenograft

from scaffold hopping from lit. PARP1/2 inh.

Bioorg. Med. Chem., Oct. 6, 2020

Lupin Ltd., Pune, IN

Structure of compound 34

“compound 34” (Lupid oral in vivo PARP1-selective polymerase inhibitor)

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