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IRE1_ kinase-binding endonuclease inhibitor
unfolded prot. response disruption for MM
from kinase library screen and SBDD
ACS Med. Chem. Lett, Oct. 16, 2020
Genentech, So. San Francisco, CA / Paraza, QC
“compound 25” (Genentech IRE1 alpha kinase-binding endonuclease inhibitor)
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