5 minute read
Jul. 27, 2022

“Compound 23” (LEO Pharma) is an Oral IL-17A Protein−Protein Interaction Modulator

compound 23

oral interleukin 17A modulator favorable in vivo PK profile in multiple species from a previous patent and SBDD J. Med. Chem. LEO Pharma Research & Early Development, Ballerup, DK

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Drug Hunter Team

Context. “Compound 23” (LEO Pharma) is an oral IL-17A protein−protein interaction modulator being developed for psoriasis and other inflammatory diseases . Like most cytokines, the involvement of IL-17A in chronic inflammatory diseases has been well-researched . IL-17A is the key cytokine that mediates psoriasis , and targeting it or its [...]

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