compound-21

oral serine beta-lactamase inh. prodrug

efficacy in murine urinary tract infect. model

from SAR of prior scaffold

Journal of Medicinal Chemistry

Shionogi, Toyonaka, JP

12. The Shionogi beta-lactamase inhibitor (BLI) cyclohexyl ester prodrug, compound 21, is a molecule with an interesting sulfinylamide motif on a strained bridgehead nitrogen amide core. The authors used…


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