© Rosalind Scientific LLC 2018-2022
© Rosalind Scientific LLC, 2018-2022
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FXR nucl. receptor + TGR5 GPCR dual agonist
dual in vivo effects at 100 mpk PO
from merger of literature agonist fragments
Sci. Rep., Apr. 28, 2021
Fuji Yakuhin Co., Ltd., Saitama, JP
The Fuji Yakuhin FXR/TGR5 non-bile acid dual agonist, compound 20p, simultaneously activates the FXR nuclear receptor and the unrelated TGR5 GPCR receptor when dosed orally in vivo. FXR has been…
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