oral ChemR23 inhibitor

Preclinical, immunology

from HTS, scaffold hopping and opt.

Bioorg. Med. Chem.

Kyowa Kirin

oral ChemR23 inhibitor - Kyowa Kirin

Context. Compound 14f (Kyowa Kirin) is an oral ChemR23 inhibitor with two acidic sites. Nominated by Bryan McKibben, this article describes a scaffold hopping exercise to address the short…

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