oral ChemR23 inhibitor

Preclinical, immunology

from HTS, scaffold hopping and opt.

Bioorg. Med. Chem.

Kyowa Kirin

oral ChemR23 inhibitor - Kyowa Kirin

Context. Compound 14f (Kyowa Kirin) is an oral ChemR23 inhibitor with two acidic sites. Nominated by Bryan McKibben, this article describes a scaffold hopping exercise to address the short…


get free samples and a Premium trial

Premium members get access to our library of hundreds of in-depth reviews on key molecules, ten new reviews each month, novel drug approval coverage, drug discovery company updates, and more: