The Genentech XIAP E3-ligase degrader, compound 10, has an interesting mechanism of action, triggering the degradation of its target (XIAP) by ubiquitylation of the small molecule. The molecule behaves as…
The Genentech XIAP E3-ligase degrader, compound 10, has an interesting mechanism of action, triggering the degradation of its target (XIAP) by ubiquitylation of the small molecule. The molecule behaves as…