oral nonbile acid FXR agonist

FGF15 induction in a BDL mouse modelSBDD

oral nonbile acid FXR agonist

J. Med. Chem.

Biocon-Bristol Myers Squibb Research and Development Center, Bangalore, IN

BMS-986399 structure

Context. BMS-986339 (BMS) is an oral farnesoid X receptor (FXR) agonist being developed for nonalcoholic steatohepatitis (NASH). Considered the master regulator of bile acid homeostasis, the nuclear receptor FXR…


get free samples and a Premium trial

Premium members get access to our library of hundreds of in-depth reviews on key molecules, ten new reviews each month, novel drug approval coverage, drug discovery company updates, and more: