BMS-986120 Chemical Structure oral PAR4 antagonist - Bristol-Myers Squibb, Princeton, NJ

oral PAR4 antagonist

Ph. II completed in thrombosis (discontinued)

HTS, potency, and PK opt.

J. Med. Chem.

Bristol-Myers Squibb, Princeton, NJ

Context. BMS-986120, (BMS) is an oral protease-activated receptor 4 (PAR4) inhibitor that was being developed for arterial thrombosis. PAR4 was long considered a redundant “backup” receptor to the more…


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