oral EGFR mutant inhibitor

Ph. I/II candidate oncology

>25k compound library screening and opt

J. Med. Chem

Blueprint Medicines, Cambridge, MA

BLU-945 Chemical Structure oral EGFR mutant inhibitor - Blueprint Medicines, Cambridge, MA

Context. BLU-945 (Blueprint Medicines) is an oral EGFR mutant inhibitor being developed for treatment-resistant non-small-cell lung cancer (NSCLC). Although three generations of EGFR TKIs are available for EGFR-mutant NSCLC,…


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